BIO-GUARD is a modular, multilateral initiative launched in early 2024 to strengthen local capacity in low- and middle-income countries (LMICs) through technology transfer and the establishment of bio-threat units.
The initiative is coordinated by the International Centre for Genetic Engineering and Biotechnology (ICGEB), which operates more than 45 state-of-the-art laboratories across Trieste, New Delhi, and Cape Town. With a global network encompassing nearly 70 member states—most of which are from the Global South—ICGEB has been a driving force in promoting research excellence and facilitating technology transfer for decades.
BIO-GUARD complements the Signature Initiative to Mitigate Biological Threats in Africa (SIMBA) and aligns with the Biological Weapons Convention (BWC), particularly Articles VII and X, which emphasize resilience against biological threats and international cooperation in the peaceful use of biological sciences.
The project is implemented in modules:
Training courses to build foundational skills in pathogen detection methods and biosecurity in low-resource settings
Two to nine months specialized training in "Biotechnologies for Pathogen Detection and BWC-Related Applications" at ICGEB’s laboratories. Fellows receive practical, hands-on training in biothreat detection, sequencing technologies, and bioinformatics, designed specifically for low-resource settings
Capacity-building initiatives to enhance early warning detection and outbreak response capabilities in fellows’ home countries through the implementation of acquired skills
BIO-GUARD is a modular, multilateral initiative launched in early 2024 to strengthen local capacity in low- and middle-income countries (LMICs) through technology transfer and the establishment of bio-threat units.
The initiative is coordinated by the International Centre for Genetic Engineering and Biotechnology (ICGEB), which operates more than 45 state-of-the-art laboratories across Trieste, New Delhi, and Cape Town. With a global network encompassing nearly 70 member states—most of which are from the Global South—ICGEB has been a driving force in promoting research excellence and facilitating technology transfer for decades. BIO-GUARD complements the Signature Initiative to Mitigate Biological Threats in Africa (SIMBA) and aligns with the Biological Weapons Convention (BWC), particularly Articles VII and X, which emphasize resilience against biological threats and international cooperation in the peaceful use of biological sciences.
The project is implemented in modules:
Training courses to build foundational skills in pathogen detection methods and biosecurity in low-resource settings.
Two to nine months specialized training in "Biotechnologies for Pathogen Detection and BWC-Related Applications" at ICGEB’s laboratories. Fellows receive practical, hands-on training in biothreat detection, sequencing technologies, and bioinformatics, designed specifically for low-resource settings
Capacity-building initiatives to enhance early warning detection and outbreak response capabilities in fellows’ home countries through the implementation of acquired skills
BIOSECURITY THREAT ASSESSMENT IN LATIN AMERICA: CICTE/OAS AND UNIVERSITY OF MARYLAND LAUNCHED NEW RESEARCH PUBLICATIONS
While the level of terrorist threats to biosecurity in Latin America remains relatively low, implementing internal measures and national biosafety and biosecurity regulations in laboratories and research centers is crucial. This is an essential step to prevent both intentional and unintentional biological accidents, mitigate risks, and prepare adequate responses in the event of an accident. Despite the experiences of the H1N1 epidemic in 2009 and the more recent COVID-19 pandemic, the region has shown vulnerability to biological threats.
The project titled "Strengthening Biosafety and Biosecurity in Latin America in line with Resolution 1540," conducted over the past years by the Inter-American Committee against Terrorism of the Organization of American States (CICTE/OAS) with the support of the European Union, aimed to lay the foundations for a stronger biosafety culture. The project also sought to create a Latin American network of expertise and strengthen biosafety and biosecurity standards and measures across the region.
In the context of the project, CICTE/OAS collaborated with the National Consortium for the Study of Terrorism and Responses to Terrorism (START) at the University of Maryland. This collaboration resulted in the development of two free online courses in Spanish for laboratory personnel and, more recently, a series of publications showcasing the findings and results of a regional survey of potential biosecurity threats in Latin America.
This two-pronged effort included a comprehensive biosecurity threat assessment of the Central and South American region and four country-level threat assessments for Chile, Colombia, Dominican Republic and Panama. These texts, in Spanish and English, provide a high-level assessment of the region for policy-focused individuals and those responsible for working in or managing the activities of laboratories, reviewing the current situation and assessing future challenges.
By way of background, a 2013 initial publication issued in Spanish, covered the scope and interrelationship of various biosafety and biosecurity concepts, existing international obligations to biosecurity through the Biological Weapons Convention (BWC) and UN Security Council Resolution 1540, the application of biosecurity across different facility types, and biosecurity risks such as proliferation, bioterrorism, agroterrorism, and bio-crime. Additionally, the publication discusses the five pillars and mechanisms of biosecurity and their application in the region.
The four countries featured in these studies have demonstrated a strong commitment to bio-risk reduction at all levels of the public and private sectors in creating safer environments. CICTE/OAS has facilitated cooperation within various funded programs, including peer review exercises and sub-regional and national workshops on biosafety and biosecurity. These reports aim to contribute to further strengthening controls and developing safer activities in handling biological agents to reduce security risks.
It is expected that these works will serve as effective tools for other countries in the region moving in a similar direction, aiding them in consolidating regulatory and control mechanisms in accordance with established international standards. CICTE/OAS expresses gratitude to the experts who participated in the project, sharing their knowledge and experiences, as well as the national authorities of all the involved countries for their trust, solid commitment, and ongoing work in strengthening compliance with international obligations.
Through these publications, CICTE/OAS reaffirms its traditional institutional support for the international disarmament and non-proliferation regime. The organization continues to express its willingness to collaborate in efforts aimed at ensuring greater regional security from multiple perspectives for all countries in the Americas.
The publications can be found and downloaded here: https://www.oas.org/ext/es/seguridad/unscr1540
One of the main focus of the EU-funded project is delivering in-person workshops. In the last six months, OAS/CICTE carried out seven face-to-face training courses for laboratory personnel and scientists from the live science fields. These workshops were designed to increase awareness of bio-risks and to strengthen knowledge on the challenges concerning biological safety and security. These courses took place, respectively, in Asuncion (Paraguay) from 17 to 21 April, Panama City (Panama) from 5 to 9 June, Santo Domingo (Dominican Republic) from 17 to 21 July, Bogotá (Colombia) from 24 to 28 July, Buenos Aires (Argentina) from 7 to 11 August, Montevideo (Uruguay) from 8 to 11 August, and Santiago (Chile) from 4 to 8 September. On average, some 30 participants from public or private institutions and research centers attended each of these courses.
Training in Santo Domingo, Dominican Republic, July 17-21, 2023 Professionals from: 12 laboratories, 7 hospitals, 4 health government agencies and 11 academia
Since its launch, BIO-GUARD has trained, in collaboration with BWC UNODA, 35 mid-career professionals from 30 countries, including 16 participants from science-and-technology-lagging countries (STLCs) and 20 women, selected from a highly competitive pool of over 800 applicants annually. Notably, a nine-month fellowship was awarded to a young woman scientist from Uganda, who is currently undergoing hands-on training at the ICGEB Molecular Virology Laboratory in Trieste.
With the support of the Italian Ministry of Foreign Affairs and International Cooperation BIO-GUARD, is expanding further its efforts to strengthen bio-preparedness and resilience in LMICs. This includes providing targeted grants to diagnostic laboratories, equipping them with essential tools and resources to integrate biosecurity measures into their routine operations.